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β cgrp  (Cusabio)


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    Cusabio β cgrp
    β Cgrp, supplied by Cusabio, used in various techniques. Bioz Stars score: 93/100, based on 23 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/β cgrp/product/Cusabio
    Average 93 stars, based on 23 article reviews
    β cgrp - by Bioz Stars, 2026-02
    93/100 stars

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    <t>CGRP</t> and cap promote cell proliferation but inhibit cell apoptosis in A549 cells grown under hyperoxic conditions. (A) Cell Counting Kit-8 assay revealed that hyperoxia inhibited A549 cell proliferation. (B) Different concentrations of CGRP (1 or 10 nM) and cap (1, 2.5, or 5 µM) promoted cell proliferation in the normal air group. (C) Different concentrations of CGRP (1, 10, or 100 nM) and cap (1, 2.5, or 5 µM) promoted cell proliferation under hyperoxia. (D) Flow cytometry revealed that hyperoxia promoted apoptosis of A549 cells, and both CGRP (10 nM) and cap (1 µM) reversed this. Data are presented as the mean ± SD of at least three repeats. *P<0.05, **P<0.01 and ***P<0.001. CGRP, calcitonin gene-related peptide; <t>cap,</t> <t>capsaicin;</t> PI, propidium iodine.
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    Calcitonin gene-related peptide <t>(CGRP)</t> content ( A , B ) and concentration ( C , D ) in trigeminal ganglia of female ( A , C ) and male rats ( B , D ). Numbers of ganglia are indicated in the bars.
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    Calcitonin gene-related peptide <t>(CGRP)</t> content ( A , B ) and concentration ( C , D ) in trigeminal ganglia of female ( A , C ) and male rats ( B , D ). Numbers of ganglia are indicated in the bars.
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    Image Search Results


    CGRP and cap promote cell proliferation but inhibit cell apoptosis in A549 cells grown under hyperoxic conditions. (A) Cell Counting Kit-8 assay revealed that hyperoxia inhibited A549 cell proliferation. (B) Different concentrations of CGRP (1 or 10 nM) and cap (1, 2.5, or 5 µM) promoted cell proliferation in the normal air group. (C) Different concentrations of CGRP (1, 10, or 100 nM) and cap (1, 2.5, or 5 µM) promoted cell proliferation under hyperoxia. (D) Flow cytometry revealed that hyperoxia promoted apoptosis of A549 cells, and both CGRP (10 nM) and cap (1 µM) reversed this. Data are presented as the mean ± SD of at least three repeats. *P<0.05, **P<0.01 and ***P<0.001. CGRP, calcitonin gene-related peptide; cap, capsaicin; PI, propidium iodine.

    Journal: Molecular Medicine Reports

    Article Title: Calcitonin gene‑related peptide alleviates hyperoxia‑induced human alveolar cell injury via the CGRPR/TRPV1/Ca2 + axis

    doi: 10.3892/mmr.2024.13234

    Figure Lengend Snippet: CGRP and cap promote cell proliferation but inhibit cell apoptosis in A549 cells grown under hyperoxic conditions. (A) Cell Counting Kit-8 assay revealed that hyperoxia inhibited A549 cell proliferation. (B) Different concentrations of CGRP (1 or 10 nM) and cap (1, 2.5, or 5 µM) promoted cell proliferation in the normal air group. (C) Different concentrations of CGRP (1, 10, or 100 nM) and cap (1, 2.5, or 5 µM) promoted cell proliferation under hyperoxia. (D) Flow cytometry revealed that hyperoxia promoted apoptosis of A549 cells, and both CGRP (10 nM) and cap (1 µM) reversed this. Data are presented as the mean ± SD of at least three repeats. *P<0.05, **P<0.01 and ***P<0.001. CGRP, calcitonin gene-related peptide; cap, capsaicin; PI, propidium iodine.

    Article Snippet: When the cell confluence reached 50–60%, the cells were treated with 10 nM CGRP (cat. no. HY-P1548A; MedChemExpress) or 1 µM capsaicin (cat. no. HY-10448; MedChemExpress), and then stimulated with hyperoxia.

    Techniques: Cell Counting, Flow Cytometry

    Calcitonin gene-related peptide (CGRP) content ( A , B ) and concentration ( C , D ) in trigeminal ganglia of female ( A , C ) and male rats ( B , D ). Numbers of ganglia are indicated in the bars.

    Journal: International Journal of Molecular Sciences

    Article Title: The Anti-Calcitonin Gene-Related Peptide (Anti-CGRP) Antibody Fremanezumab Reduces Trigeminal Neurons Immunoreactive to CGRP and CGRP Receptor Components in Rats

    doi: 10.3390/ijms241713471

    Figure Lengend Snippet: Calcitonin gene-related peptide (CGRP) content ( A , B ) and concentration ( C , D ) in trigeminal ganglia of female ( A , C ) and male rats ( B , D ). Numbers of ganglia are indicated in the bars.

    Article Snippet: Rat α-CGRP, β-CGRP, monoclonal , Mouse , Santa Cruz Biotechnology, Heidelberg, Germany www.scbt.com ; last access Aug 2023 , Sc-57053/CGRP (4901) , 1:10.

    Techniques: Concentration Assay

    Correlation of the measured CGRP content and the calculated CGRP concentration in 48 trigeminal ganglia ( r x,y , correlation coefficient).

    Journal: International Journal of Molecular Sciences

    Article Title: The Anti-Calcitonin Gene-Related Peptide (Anti-CGRP) Antibody Fremanezumab Reduces Trigeminal Neurons Immunoreactive to CGRP and CGRP Receptor Components in Rats

    doi: 10.3390/ijms241713471

    Figure Lengend Snippet: Correlation of the measured CGRP content and the calculated CGRP concentration in 48 trigeminal ganglia ( r x,y , correlation coefficient).

    Article Snippet: Rat α-CGRP, β-CGRP, monoclonal , Mouse , Santa Cruz Biotechnology, Heidelberg, Germany www.scbt.com ; last access Aug 2023 , Sc-57053/CGRP (4901) , 1:10.

    Techniques: Concentration Assay

    Typical examples of corresponding images used for cell counting of neurons immunopositive for CGRP, receptor activity modifying protein 1 (RAMP1), calcitonin receptor-like receptor (CLR) and receptor component protein (RCP) in the V1 region ( D , E ) and the V2 region ( A – C , F – I , K ). ( A , D , I ) represent ganglion sections of animals treated with control antibody, ( B , E , K ) are from animals treated with fremanezumab, ( C ) shows part of a control section without primary antibody. ( H ) is an overlay of ( F , G ) showing co-localization of CLR and RCP immunofluorescence. Arrows point to neurons classified as strongly immunopositive, arrowheads mark exemplary neurons regarded as weakly positive; stars in ( A – C ) show unstained neurons, which are only visible in high brightness or indicated by their surrounding satellite cells (blue DAPI staining). Red fluorescence is produced by a secondary antibody conjugated with Alexa 555, green fluorescence with Alexa 488.

    Journal: International Journal of Molecular Sciences

    Article Title: The Anti-Calcitonin Gene-Related Peptide (Anti-CGRP) Antibody Fremanezumab Reduces Trigeminal Neurons Immunoreactive to CGRP and CGRP Receptor Components in Rats

    doi: 10.3390/ijms241713471

    Figure Lengend Snippet: Typical examples of corresponding images used for cell counting of neurons immunopositive for CGRP, receptor activity modifying protein 1 (RAMP1), calcitonin receptor-like receptor (CLR) and receptor component protein (RCP) in the V1 region ( D , E ) and the V2 region ( A – C , F – I , K ). ( A , D , I ) represent ganglion sections of animals treated with control antibody, ( B , E , K ) are from animals treated with fremanezumab, ( C ) shows part of a control section without primary antibody. ( H ) is an overlay of ( F , G ) showing co-localization of CLR and RCP immunofluorescence. Arrows point to neurons classified as strongly immunopositive, arrowheads mark exemplary neurons regarded as weakly positive; stars in ( A – C ) show unstained neurons, which are only visible in high brightness or indicated by their surrounding satellite cells (blue DAPI staining). Red fluorescence is produced by a secondary antibody conjugated with Alexa 555, green fluorescence with Alexa 488.

    Article Snippet: Rat α-CGRP, β-CGRP, monoclonal , Mouse , Santa Cruz Biotechnology, Heidelberg, Germany www.scbt.com ; last access Aug 2023 , Sc-57053/CGRP (4901) , 1:10.

    Techniques: Cell Counting, Activity Assay, Control, Immunofluorescence, Staining, Fluorescence, Produced

    Fraction of the number of neurons immunoreactive to CGRP in trigeminal ganglia of rats treated with control antibody versus fremanezumab. The dark colours indicate strongly immunopositive, and the light colours weakly, immunopositive neurons. The numbers of sections used for counting are indicated in the bars.

    Journal: International Journal of Molecular Sciences

    Article Title: The Anti-Calcitonin Gene-Related Peptide (Anti-CGRP) Antibody Fremanezumab Reduces Trigeminal Neurons Immunoreactive to CGRP and CGRP Receptor Components in Rats

    doi: 10.3390/ijms241713471

    Figure Lengend Snippet: Fraction of the number of neurons immunoreactive to CGRP in trigeminal ganglia of rats treated with control antibody versus fremanezumab. The dark colours indicate strongly immunopositive, and the light colours weakly, immunopositive neurons. The numbers of sections used for counting are indicated in the bars.

    Article Snippet: Rat α-CGRP, β-CGRP, monoclonal , Mouse , Santa Cruz Biotechnology, Heidelberg, Germany www.scbt.com ; last access Aug 2023 , Sc-57053/CGRP (4901) , 1:10.

    Techniques: Control

    Fraction of the number of neurons immunoreactive to the CGRP receptor components CLR, RAMP1 and RCP in trigeminal ganglia of rats treated with control antibody versus fremanezumab. The dark colours indicate strongly immunopositive and the light colours weakly immunopositive neurons. The numbers of sections used for counting are indicated in the bars.

    Journal: International Journal of Molecular Sciences

    Article Title: The Anti-Calcitonin Gene-Related Peptide (Anti-CGRP) Antibody Fremanezumab Reduces Trigeminal Neurons Immunoreactive to CGRP and CGRP Receptor Components in Rats

    doi: 10.3390/ijms241713471

    Figure Lengend Snippet: Fraction of the number of neurons immunoreactive to the CGRP receptor components CLR, RAMP1 and RCP in trigeminal ganglia of rats treated with control antibody versus fremanezumab. The dark colours indicate strongly immunopositive and the light colours weakly immunopositive neurons. The numbers of sections used for counting are indicated in the bars.

    Article Snippet: Rat α-CGRP, β-CGRP, monoclonal , Mouse , Santa Cruz Biotechnology, Heidelberg, Germany www.scbt.com ; last access Aug 2023 , Sc-57053/CGRP (4901) , 1:10.

    Techniques: Control

    Experimental timeline for measurements of CGRP content ( A ) and preparation for immunohistochemistry ( B ) after injection of fremanezumab or isotype control antibody at day 0.

    Journal: International Journal of Molecular Sciences

    Article Title: The Anti-Calcitonin Gene-Related Peptide (Anti-CGRP) Antibody Fremanezumab Reduces Trigeminal Neurons Immunoreactive to CGRP and CGRP Receptor Components in Rats

    doi: 10.3390/ijms241713471

    Figure Lengend Snippet: Experimental timeline for measurements of CGRP content ( A ) and preparation for immunohistochemistry ( B ) after injection of fremanezumab or isotype control antibody at day 0.

    Article Snippet: Rat α-CGRP, β-CGRP, monoclonal , Mouse , Santa Cruz Biotechnology, Heidelberg, Germany www.scbt.com ; last access Aug 2023 , Sc-57053/CGRP (4901) , 1:10.

    Techniques: Immunohistochemistry, Injection, Control

    List of antibodies.

    Journal: International Journal of Molecular Sciences

    Article Title: The Anti-Calcitonin Gene-Related Peptide (Anti-CGRP) Antibody Fremanezumab Reduces Trigeminal Neurons Immunoreactive to CGRP and CGRP Receptor Components in Rats

    doi: 10.3390/ijms241713471

    Figure Lengend Snippet: List of antibodies.

    Article Snippet: Rat α-CGRP, β-CGRP, monoclonal , Mouse , Santa Cruz Biotechnology, Heidelberg, Germany www.scbt.com ; last access Aug 2023 , Sc-57053/CGRP (4901) , 1:10.

    Techniques: